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| A superior diagnostic tool – Nerve Fiber Indicator (NFI) |
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NFI distribution in normal and glaucoma subjects (N=152)
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| 95% of the normal eyes had an NFI ≤ 35 for ECC. VCC has similar performance. (CZM study, data on file.) |
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A superior diagnostic tool – Nerve Fiber Indicator (NFI)
- An artificial intelligence algorithm based on the entire RNFL profile.
- Though not definitive, the NFI is a single ordinal number indicating likelihood that the polarimetric retinal nerve fiber layer is normal.
- Proven performance in assessing early glaucoma.1,2
- The NFI is not intended to be used as the sole basis of diagnosis for disease.
| 1 | Medeiros FA, Vizzeri G, Zangwill LM, Alencar LM, Sample PA, and Weinreb RN. Comparison of retinal nerve fiber layer and optic disc imaging for diagnosing glaucoma in patients suspected of having the disease. Ophthalmology, 2008; 115: 1340-6. |
| 2 | Medeiros FA, Zangwill LM, et al. Use of Progressive Glaucomatous Optic Disk Change as the Reference Standard for Evaluation of Diagnostic Tests in Glaucoma. American Journal of Ophthalmology 2005; 139:1010-1018. |
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