In the Words of Surgeons:
 Walter Stummer, M.D.
Associate Professor and Vice Chairman, Department of Neurosurgery, University of Düsseldorf, Düsseldorf, Germany
(mpeg1, 8.7 MB)
Volker Seifert, M.D., Ph.D.
Professor and Chairman, Department of Neurosurgery, Johann Wolfgang Goethe University, Frankfurt, Germany
(mpeg1, 3.5 MB)
Walter Stummer, M.D.,
Associate Professor and Vice Chairman, Department of Neurosurgery, University of Düsseldorf, Düsseldorf, Germany 1):
“[…] We have shown that use of 5-aminolevulinic acid leads to a higher frequency of complete resections of contrast-enhancing tumours on early postoperative MRI, translating into higher progression-free survival, than does conventional microsurgery guided by white light. Postoperative Karnofsky performance score, neurological status, and toxic effects were much the same for both groups, showing fluorescence-guided surgery with 5-aminolevulinic acid to be safe.”
Jörg-Christian Tonn, M.D., Ph.D.,
Director, Neurosurgical Clinic and Polyclinic, University of Munich Hospital, Munich, Germany:
“The normal white light illumination is often insufficient for displaying the tumor edges of glioblastomas IV. After the administration of 5-ALA, the entire tumor glows red and becomes very clear in the fluorescence mode. This is a very helpful indicator and assists the surgeon.”
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